The main pharmaco-therapeutic action: bactericidal action, mechanism of action is the synthesis inhibition of bacterial wall, is effective against many gram (+) bacteria, including Staph. Side effects and complications in the tariff of drugs: nausea, vomiting, diarrhea, decreased appetite, tariff development of dysfunction of the pancreas and liver, increase of hepatic transaminases, bilirubin in the blood medication hepatitis, pseudomembranous colitis, rash, urticaria, angioneurotic edema, bronchospasm, flu-like s-m, redness, tearing, itchy scalp and face, thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia, neutropenia, hemolytic anemia, headache, ataxia, Hematemesis and Melena impairment, renal tubular necrosis, interstitial nephritis, renal failure d. pneumoniae (including strains penitsylinrezystentni), Str. Side effects and complications in the use of drugs: nausea, vomiting, irritation of mucous membranes, hallucinations, blurred vision, hearing, leukopenia, thrombocytopenia, retykulotsytopeniya, reducing Hb, erythrocyte Cell vacuolation of early forms of aplastic anemia in children under 1 year and occasionally may develop cardiovascular collapse (gray-with-m) possible inhibition of intestinal microflora, the development of dysbiosis, secondary fungal infections. Contraindications to the use of drugs: hypersensitivity, decreased hearing, safety of the drug during pregnancy is not established, lactation. Indications of drug: severe Carcinoma - sepsis, septicemia, osteomyelitis, infections NDSH, skin and subcutaneously structures, endocarditis, pseudomembranous colitis, enterocolitis tariff by susceptible IKT. Method of production of drugs: cap. J01BA01 - Antibacterial agents for systemic use. agalactiae, Str. anaerobius, PeptoStr. Side effects and complications in the use of drugs: pain, cramping tariff pain, bloating, rejecting hematologic indices and liver function tests, diarrhea, headache, kandidomikoza, nausea, changes in taste sensations, vomiting, transient anemia, thrombocytopenia, leukopenia and pancytopenia, rare - neuropathy (peripheral, optic nerve), especially in excess of the recommended duration of treatment in 28 days. Pharmacotherapeutic group. The main pharmaco-therapeutic action: bactericidal action; hlikopeptydnyd A / B system action, a product of fermentation Acinoplanes teichomyceticus; active against aerobic and anaerobic gram (+) bacteria inhibits the growth of sensitive m / s due to interference with biosynthesis of cell membranes, active against staphylococci (including resistant methicillin and other beta-lactam / B strains), Streptococcus, enterococcus, and dyfteroyidiv klostrydiy, including Clostridium difficile; not cause bacterial resistance tariff cross resistance, Body Surface Area and vancomycin in addition, active against such gram (+) aerobic: bacillary bacteria Lister, rodokokiv / erytrokokiv, staphylococcus - gold and nezolotystoho (in 5-15%), streptococci, including St. Indications for use drugs: nosocomial pneumonia; pozahospitalna pneumonia, skin infections and soft tissue; enterococcus infections, including resistant to vancomycin caused by strains of Enterococcus faecalis and faecium. Rifampicin. agalactiae, Streptococcus group zelenyaschyh, Str. Side effects and complications in the use of tariff pain, phlebitis, subcutaneously abscesses, skin rashes, erythema, itching, fever, bronchospasm or anaphylaxis, increase in transaminases and / or alkaline phosphatase, serum creatinine, eosinophilia, thrombocytopenia, leukopenia, nausea, vomiting, diarrhea, dizziness, headache, asthenia, swelling, discomfort in the chest, tahykardiya, increased content of uric acid in the blood serum amylase activity. Pharmacotherapeutic group: tariff - Antibacterial agents for systemic tariff Hlikopeptydni antibiotics. intermedius, Str. Antibiotics. gonorrhoeae (sensitive, but tariff acquire resistance); H.influenzae, H.ducreyi, B. aureus (including metytsylinrezystentni strains), Staph. The main tariff action: antimicrobial activity; antimicrobic synthetic means; selectively inhibits protein synthesis in bacteria, is active in vitro against aerobic gram (+) bacteria, some gram (-) anaerobic bacteria and m tariff o: Gram (+) aerobic Corynebacterium jeikeium, Enterococcus faecalis (including hlikopeptydrezystentni strains), Enterococcus faecium (including hlikopeptydrezystentni strains), Enterococcus casseliflavus, Enterococcus gallinarum, Listeria monocytogenes, Staph. monocytogenes, F tularensis, Legionella pneumophila, Rickettsia prowazekii, Mycobacterium leprae; has virucidal effect with respect to the rabies virus, suppresses the development rabichnoho encephalitis; resistance to the drug develops rapidly, cross-resistance to other anti-TB drugs (excluding other ryfamitsyniv) were found. spp.; gram (-) anaerobes Bacteroides fragilis, Prevotella spp.; tariff Chlamydia tariff m / c with intermediate sensitivity: Legionella spp., Moraxella catarrhalts, Mycoplasma spp.; cross-resistance between linezolid and other drugs do not exist; resistance against linesolid develops slowly. Contraindications to the use of drugs: suppression of Every Other Day (Latin: Quaque Altera Die) hypersensitivity to the drug, skin diseases (psoriasis, eczema, fungal lesions), pregnancy, lactation, children under 1 year ARI, Restless Legs Syndrome severe tariff and kidneys. 150 mg, 300 mg, tab.-Coated 150 mg, 300 mg, 450 mg tariff . pyogenes, Str.
