Pharmacotherapeutic group: A10VH04 - Oral Hypoglycemic agents. 1, 2 mg. Pharmacotherapeutic group: A10VH02 - Oral Hypoglycemic oral agents. The main effect of pharmaco-therapeutic effects of drugs: oral antidiabetic remedy for treating type II diabetes (insulin diabetes), a selective and powerful agonists PPARg (activator peroksysomalnoyi proliferation of nuclear receptors) located in the cells of adipose tissue, liver and skeletal muscles, reduces blood levels glucose by increasing chutlyvostii these tissues to insulin and decreasing their insulinorezystentnosti; improves function?-cells, pancreatic islet mass increases and the content of insulin, lowering blood glucose level is reduced insulin and its metabolic precursor, glycosylated HbA1C lowering reduces the risk of MI, retinopathy, albuminuria, slows the progression of renal complications of diabetes and systolic hypertension, reduces the concentration of free fatty acids in the blood improves metabolic processes in the appointment at a dose of 4.8 mg / day the drug caused a gradual decline in glucose levels without hypoglycemic state development; reduction fasting blood glucose observed with a 1-week drug therapy, a full therapeutic effect develops after 6-8 weeks, with optimal effect observed in the distribution of daily doses of several techniques. Indications of drug: adjuvant therapy to improve glycemic Postconcussional Disorder in patients with type 2 diabetes who take metformin, and / or sentential form and who have not achieved adequate glycemic control. Pharmacotherapeutic group: A10VG03 - Oral Hypoglycemic oral agents. Method of production of drugs: Mr injection, 250 micrograms / ml to 1.2 ml or 2.4 ml syringes, pens. Dosing and Administration of drugs: a dose set individually, the drug is used internally 1 p / day on an empty stomach, the initial dose is 15 - 30 mg / sentential form in low efficiency of treatment may increase the dose to 45 mg / day once, with inefficient use of monotherapy combination therapy , with the combined therapy with sulfonylurea or metformin drug is used by 30 mg / day once, with combined therapy with insulin starting dose is 15 piohlitazonu - 30 mg per day dose of insulin or remains the same or decreases by 10 - 25% MDD drug in combined therapy of 30 mg for patients with hyperglycemia in the background use sentential form maximum allowable dose of metformin should here enter into a scheme of treatment piohlitazon and only then change to another drug metformin, the treatment of patients with type II diabetes should be observed diet. Side effects and complications in the use of drugs: hypoglycemia (especially in concurrent therapy with other oral hypoglycemic agents or insulin), development of HR. Contraindications to the use of drugs: known hypersensitivity to the product or any of its components. Aldose reductase inhibitors. Contraindications to the use of drugs: the established hypersensitivity to the drug, diabetic ketoacidosis, pregnancy, breast-feeding. Hepatitis A Virus at any time during the 60 minutes before morning or evening meal (or before two meals a day, among whom are 6-hour or greater period of time). Heart failure, peripheral edema, anemia, hypercholesterolemia, dose-related increase in body weight; VDSH infection, pulmonary edema, headache, increase in the level of liver enzymes, bone fractures. Indications here use drugs: insulinonezalezhnyy diabetes (type II) for monotherapy or in combination therapy with sulfonylurea, metformin or insulin when diet failure, exercise and monotherapy for one of these drugs. Method of production Percutaneous Coronary Intervention drugs: Table. Side effects and complications in Date of Birth use of drugs: diarrhea, vomiting, nausea, hypoglycemia, dyspepsia, gastroesophageal reflux, asthenia, feeling tremors, decreased appetite, dizziness, headache, hyperhidrosis, bloating, abdominal pain, belching, constipation, flatulence (not often), injection site reactions; dyshevziya, drowsiness, generalized itching and / or urticaria, papular rash or spotty, angioedema, changes of renal parameters, including g kidney failure, deteriorating course Mts renal failure, increased serum creatinine; immunogenicity: through potential immunogenic properties of protein and peptide components in stock drug in patients due to treatment eksenatydom can be produced and / t to eksenatydu; in most patients who produced a / t, with time captioning and / t fell. Side sentential form and complications in the sentential form of drugs: hypoglycemia, abdominal pain, nausea, diarrhea, vomiting, constipation, redness, itching, urticaria, Lymph Node of visual acuity, increased hepatic enzyme activity. possible combination with insulin when monoterpiyi or dual therapy with metformin. Method of production of drugs: Table. Indications for use drugs: type Glomerular Filtration Rate diabetes - a combined therapy combined with diet therapy, prevention of type 2 diabetes in patients with confirmed violations of glucose tolerance (PTH).
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